Comparison of oxidative metabolism in starved, fat-fed and carbohydrate-fed rats

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Comparison of oxidative metabolism in starved, fat-fed and carbohydrate-fed rats.

1. Rats were starved for 48hr. or fed for 1 week on a high-fat or a high-carbohydrate diet. The effects of these dietary alterations on the rate of production of (14)CO(2) from trace amounts of [U-(14)C]glucose, [1-(14)C]palmitate or [1-(14)C]acetate administered intravenously were studied. 2. The oxidation of [(14)C]glucose was most rapid in the carbohydrate-fed condition and was decreased sig...

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Carbohydrate sparing and storage during the starved to fed transition.

Starvation is characterized by adaptive mechanisms which ensure that an adequate supply of glucose is maintained for tissues which have an obligatory requirement for it. Dietary carbohydrate is replaced by glucose produced via the mobilization of glycogen stores and/or gluconeogenesis. Increases in lipolysis and ketogenesis ultimately result in the increased provision of alternative non-carbohy...

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Phospholipid metabolism in the lung of fat-fed rats.

Phospholipid metabolism in the lung was studied because the lung was the first organ at which the ingested lipids arrived. It was revealed in this study that the lung contained phosphatidyl cho-line, ethanolamine, phosphoinositol, sphingomyelin and lysolecithin, that the amount of phosphatidyl serine were very small in the lung, and that a phosphatidic acid was discovered in the lung after the ...

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Alterations in adipose-tissue pyruvate dehydrogenase activity in starved, fat-fed and diabetic rats.

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Metabolism of R- and S-1,3-butanediol in perfused livers from meal-fed and starved rats.

The metabolism of millimolar concentrations of R- or S-1,3-butanediol has been studied in perfused livers from fed and starved rats. Protocols were designed to measure in the same experiment (i) uptake of the diol, (ii) the contribution of the diol to ketogenesis, (iii) the contribution of the diol to total fatty acid plus sterol synthesis, and (iv) conversion of S-1,3-butanediol into S-3-hydro...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1967

ISSN: 0006-2936

DOI: 10.1042/bj1030400